
Each box of 10 vials carries a Peptworks label and a unique QR → the batch CoA (HPLC + heavy metals), verified by a third party. Checkable by you and your customers.
🔗 peptworks.com/coaCagriSema
| Vials of this reference | Format | €/vial | This product ×10 |
|---|---|---|---|
| 4–9 | 4-pack | €71,90 | €288 |
| 10+ | Box · 10 or more | €45,00 | €450 |
Each reference is priced by its own quantity: a 4-pack, or the box price from 10 vials. No volume tiers: free shipping from €500 per order (€24.90 below), inside the EU with no customs.
What is — CagriSema
CagriSema is a co-formulated research reagent combining cagrilintide (a long-acting amylin analogue) and semaglutide (a GLP-1 receptor agonist), supplied as a lyophilized 10 mg vial in a 5+5 mg split. Peptworks distributes it B2B as a laboratory research chemical for Research Use Only (RUO): it is not a medicine, supplement, cosmetic or medical device, and it is not intended for human or animal consumption. Vials are available as unbranded bulk (white-label), shipped from EU stock, with each batch documented by an independent Certificate of Analysis.
As a research substrate, CagriSema pairs two distinct receptor-signalling tools. Semaglutide is studied as an agonist at the glucagon-like peptide-1 (GLP-1) receptor, a class-B G-protein-coupled receptor implicated in incretin signalling pathways. Cagrilintide is studied as an analogue acting at amylin and calcitonin receptor complexes. The co-formulation is used in preclinical and in-vitro work to investigate combined or complementary engagement of these two pathways within a single defined reagent, enabling comparison against single-target reference compounds. All mechanistic description here refers to receptor pharmacology in laboratory research models, not to any effect in humans.
Research
- Incretin and GLP-1 receptor signalling pharmacology in vitro
- Amylin and calcitonin receptor complex research
- Comparative dual-pathway versus single-agonist metabolic research in animal models
- Food-intake and body-weight endpoint studies in rodent models
- Receptor-binding and dose-response assay development
- Analytical method development, HPLC characterization and formulation/stability studies
Advantages
- Enables preclinical study of combined amylin-analogue and GLP-1 receptor agonist activity within a single defined reagent
- Supports dose-ranging and receptor-occupancy experiments in cell-based and animal metabolic models
- Facilitates comparative research against single-agonist reference arms such as semaglutide-only or cagrilintide-only
- Suitable for analytical method development and formulation or stability workflows requiring a defined lyophilized substrate
- Consistent purity of at least 98% HPLC per batch supports reproducibility across research runs
- Per-batch CoA and QR traceability streamline documentation for research distributors and white-label catalogues
Safety
- Delayed gastric emptying reported in animal feeding-behaviour models for GLP-1 and amylin analogues
- Reduced food intake and lowered body-weight endpoints observed in rodent metabolic studies
- Transient gastrointestinal-motility changes described in the preclinical literature for these peptide classes
- Dose-dependent tolerability observations noted in animal-model reports
- As a research reagent handled by trained personnel only; these are literature observations in research models, not human safety guidance
Ideal for
- Research distributors and laboratories sourcing GLP-1 class reagents in bulk within the EU
- White-label brands building a metabolic-research peptide catalogue
- Preclinical metabolic and receptor-pharmacology research programmes
- Analytical and QC laboratories developing HPLC or purity methods
- Comparative studies requiring a dual amylin/GLP-1 substrate against single-target references
This product is a laboratory reagent supplied strictly for research. It is not a medicine, food or supplement and is not for human or veterinary use. It must be handled by qualified professionals under laboratory conditions.
GLP-1 research peptides compared
Receptor targets as described in the research literature. Research use only.
| Peptide | Receptor targets | Vial | Box (10+) | 4-pack |
|---|---|---|---|---|
| Semaglutide | GLP-1R | 5 mg | €18,00 | €28,90 |
| Tirzepatide | GLP-1R + GIPR | 10 mg | €25,00 | €39,90 |
| Retatrutide | GLP-1R + GIPR + GCGR | 10 mg | €35,00 | €55,90 |
| Survodutide | GLP-1R + GCGR | 10 mg | €88,00 | €140,90 |
| Cagrilintide | AMYR / CTR (amylin) | 10 mg | €55,00 | €87,90 |
| CagriSema | AMYR / CTR + GLP-1R | 10 mg (5+5) | €45,00 | €71,90 |
Read the guide: retatrutide vs tirzepatide, the key differences →
Frequently asked questions
Where can I buy CagriSema in bulk in the EU?
Peptworks supplies CagriSema (cagrilintide + semaglutide) wholesale from stock already inside the EU, so orders ship intra-community in 3-5 business days with no customs. It is sold B2B only, for research use, either as unbranded bulk vials (white-label). Orders start from a 4-vial pack per reference.
What is the wholesale price per vial of CagriSema?
CagriSema 10mg(5+5) has two public per-vial prices: €71.90 in a 4-vial pack and €45.00 from 10 vials of this reference (box price). There are no volume tiers. Shipping is free on orders from €500 (€24.90 below), inside the EU with no customs.
Do you offer CagriSema as white-label?
Yes, in the white-label sense: CagriSema comes in unbranded vials, with no brand on the vial, so you can resell it under your own label. Peptworks does not print or apply labels. Every batch is tested by an independent lab and ships from EU stock with no customs.
What is the minimum order for CagriSema?
The minimum is a 4-vial pack per reference; from 10 vials of a reference the lower box price applies. Vials ship in boxes of 10. There are no volume tiers, and orders from €500 ship free.
How is the Certificate of Analysis verified?
Each box carries a unique QR code linking to the Certificate of Analysis for that exact batch, independently verifiable through Peptworks. Every batch is tested to at least 98% HPLC purity with an independent CoA covering HPLC and heavy metals. This traceability lets your own customers confirm authenticity per batch.
How does payment and shipping work for B2B orders?
Payment is in crypto: USDC or USDT (Polygon or Base) or Bitcoin — paying in crypto is what keeps our prices this tight, with no card or bank fees. no card payment is taken on the site. Because stock is held inside the EU, orders move as intra-community shipments in 3-5 business days with no customs clearance. The full site is available in 10 languages (ES, EN, DE, FR, PT, IT, NL, PL, CS, EL).