Each box of 10 vials carries a Peptworks label and a unique QR → the batch CoA (HPLC + heavy metals), verified by a third party. Checkable by you and your customers.
🔗 peptworks.com/coaMelanotan I
| Vials of this reference | Format | €/vial | This product ×10 |
|---|---|---|---|
| 4–9 | 4-pack | €31,90 | €128 |
| 10+ | Box · 10 or more | €20,00 | €200 |
Each reference is priced by its own quantity: a 4-pack, or the box price from 10 vials. No volume tiers: free shipping from €500 per order (€24.90 below), inside the EU with no customs.
What is — Melanotan I
Melanotan I (also known as afamelanotide, [Nle4, D-Phe7]-alpha-MSH or NDP-alpha-MSH) is a synthetic 13-amino-acid analog of alpha-melanocyte-stimulating hormone (alpha-MSH), supplied by Peptworks as a lyophilized 10 mg vial for Research Use Only. Substitutions of norleucine at position 4 and D-phenylalanine at position 7, together with terminal modifications, give the molecule greater enzymatic stability and prolonged receptor occupancy than native alpha-MSH. It is offered B2B from EU stock as unbranded bulk vials (white-label), at >=98% HPLC purity with an independent per-batch Certificate of Analysis. It is not a medicine, supplement, cosmetic or medical device, and is not for human or animal consumption.
In research models, Melanotan I acts as a potent agonist at the melanocortin-1 receptor (MC1R); it is a non-selective melanocortin agonist that also binds other receptor subtypes (MC3R-MC5R), with high activity at MC1R. Receptor activation stimulates the intracellular cyclic AMP (cAMP) signaling cascade in melanocyte cultures, which in turn influences microphthalmia-associated transcription factor (MITF) activity and tyrosinase, the rate-limiting enzyme in melanin synthesis. In cell-based studies this pathway is associated with increased eumelanin production relative to pheomelanin. All description here refers strictly to in-vitro and preclinical experimental systems, not to any effect in humans.
Research
- Melanocortin receptor (MC1R) pharmacology and receptor-ligand binding studies
- Melanogenesis signaling in cultured melanocytes (cAMP-MITF-tyrosinase axis)
- Eumelanin versus pheomelanin synthesis in cell models
- Photoprotection and UV-response research in cell and animal models
- Structure-activity relationship studies of alpha-MSH analogs
- Peptide stability and enzymatic-degradation resistance assays
Advantages
- Serves as a well-characterized reference agonist at the melanocortin-1 receptor (MC1R) for melanocortin pathway research
- Enhanced enzymatic stability and prolonged receptor occupancy versus native alpha-MSH in experimental systems
- In vitro association with increased melanin (eumelanin) synthesis in melanocyte cultures
- Useful positive control in structure-activity relationship and receptor-binding assays
- Consistent >=98% HPLC purity supports reproducible experimental conditions across batches
Safety
- As a research reagent handled in the laboratory, Melanotan I has no established human safety profile from Peptworks and is not administered to people or animals
- Research literature on melanocortin analogs commonly discusses pigmentation-related endpoints and receptor cross-reactivity as experimental observations, not human outcomes
- Standard laboratory handling precautions for lyophilized peptides apply (avoid inhalation, skin and eye contact; reconstitute and store per protocol)
- No claims are made regarding safety or effects in humans; the product is Research Use Only
Ideal for
- Academic and commercial laboratories studying MC1R and melanocortin signaling
- Melanogenesis and pigmentation cell-culture research
- Photobiology and UV-response experimental models
- Structure-activity relationship and peptide-stability method development
- Resellers building an EU-stock research-peptide catalog in bulk or white-label
This product is a laboratory reagent supplied strictly for research. It is not a medicine, food or supplement and is not for human or veterinary use. It must be handled by qualified professionals under laboratory conditions.
Frequently asked questions
Where can I buy Melanotan I in bulk in the EU?
Peptworks supplies Melanotan I (10 mg lyophilized vials) wholesale from stock already inside the EU, so orders ship intra-community in 3-5 business days with no customs. It is a B2B research-reagent supply for resellers and labs, not a consumer shop. Orders start from a 4-vial pack per reference. Sold for Research Use Only (RUO).
What is the wholesale price per vial of Melanotan I?
Melanotan I 10mg has two public per-vial prices: €31.90 in a 4-vial pack and €20.00 from 10 vials of this reference (box price). There are no volume tiers. Shipping is free on orders from €500 (€24.90 below), inside the EU with no customs. Payment is in crypto: USDC or USDT (Polygon or Base) or Bitcoin — paying in crypto is what keeps our prices this tight, with no card or bank fees. there is no card checkout.
Do you offer Melanotan I as white-label?
Yes, in the white-label sense: Melanotan I comes in unbranded vials, with no brand on the vial, so you can resell it under your own label. Peptworks does not print or apply labels. Every batch is tested by an independent lab and ships from EU stock with no customs.
What is the minimum order for Melanotan I?
The minimum is a 4-vial pack per reference; from 10 vials of a reference the lower box price applies. Vials ship in boxes of 10. There are no volume tiers, and orders from €500 ship free.
How is the Certificate of Analysis verified?
Every batch ships with an independent per-batch Certificate of Analysis (CoA) covering HPLC purity (>=98%) and heavy metals. The box carries the Peptworks label plus a unique QR that links to that specific batch's CoA, verifiable through Peptworks. This lets your own downstream buyers confirm authenticity per batch.
Is Melanotan I from Peptworks for human use?
No. Melanotan I is supplied strictly as a laboratory research reagent, Research Use Only (RUO). It is not a medicine, supplement, cosmetic or medical device and is not for human or animal consumption. Peptworks sells B2B to resellers and research organisations only, not to end users.